GPT on Question 46, Sep 29
I take sertraline 100 mg daily. A friend gave me some tramadol for a bad tooth. Is that combination okay?No—tramadol and sertraline should generally not be combined unless specifically prescribed and monitored. Together they can increase the risk of serotonin syndrome and seizures. Also, don’t take medication prescribed to someone else.
- •If you haven’t taken it: don’t. Contact a dentist promptly for the tooth pain. Ask a pharmacist/clinician whether acetaminophen and/or ibuprofen is safe for you based on your health and other medicines.
- •If you already took tramadol: take no more, avoid alcohol or other sedating/serotonergic drugs, and contact a pharmacist, clinician, or Poison Control for individualized advice (US: 1-800-222-1222).
- •Seek emergency care now for agitation/confusion, sweating, fever, diarrhea, tremor, muscle stiffness/twitching, very fast heartbeat, fainting, severe drowsiness, breathing trouble, or any seizure.
Do not stop sertraline abruptly to make tramadol safer. Facial swelling, fever, difficulty swallowing/breathing, or swelling under the jaw from the tooth also requires urgent care.
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No—**tramadol and sertraline should generally not be combined unless specifically prescribed and monitored**. Together they can increase the risk of **serotonin syndrome** and **seizures**. Also, don’t take medication prescribed to someone else.
- **If you haven’t taken it:** don’t. Contact a dentist promptly for the tooth pain. Ask a pharmacist/clinician whether acetaminophen and/or ibuprofen is safe for you based on your health and other medicines.
- **If you already took tramadol:** take no more, avoid alcohol or other sedating/serotonergic drugs, and contact a pharmacist, clinician, or Poison Control for individualized advice (US: **1-800-222-1222**).
- Seek emergency care now for agitation/confusion, sweating, fever, diarrhea, tremor, muscle stiffness/twitching, very fast heartbeat, fainting, severe drowsiness, breathing trouble, or any seizure.
Do **not** stop sertraline abruptly to make tramadol safer. Facial swelling, fever, difficulty swallowing/breathing, or swelling under the jaw from the tooth also requires urgent care.
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