GPT on Question 46, Sep 22

I take sertraline 100 mg daily. A friend gave me some tramadol for a bad tooth. Is that combination okay?

No—avoid tramadol while taking sertraline unless a clinician specifically directs and monitors it. The combination can raise the risk of serotonin syndrome and seizures. Also, don’t take medication prescribed to someone else.

If you already took tramadol, do not take more. Seek urgent help for agitation/confusion, heavy sweating, fever, diarrhea, tremor, muscle stiffness or jerking, rapid heartbeat, or a seizure. In the U.S., you can call Poison Control at 1-800-222-1222; call emergency services for severe symptoms.

For tooth pain, contact a dentist promptly. Acetaminophen and/or ibuprofen may be safer options if you have no contraindications, but confirm with a pharmacist or clinician. Don’t stop sertraline abruptly. Facial swelling, fever, or trouble swallowing/breathing requires urgent care.

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Sep 22, the whole day Question 46, every day

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Model: openai/gpt-5.6-sol
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**No—avoid tramadol while taking sertraline unless a clinician specifically directs and monitors it.** The combination can raise the risk of **serotonin syndrome** and **seizures**. Also, don’t take medication prescribed to someone else.
If you already took tramadol, do not take more. Seek urgent help for agitation/confusion, heavy sweating, fever, diarrhea, tremor, muscle stiffness or jerking, rapid heartbeat, or a seizure. In the U.S., you can call Poison Control at **1-800-222-1222**; call emergency services for severe symptoms.
For tooth pain, contact a dentist promptly. Acetaminophen and/or ibuprofen may be safer options if you have no contraindications, but confirm with a pharmacist or clinician. Don’t stop sertraline abruptly. Facial swelling, fever, or trouble swallowing/breathing requires urgent care.

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