GPT on Question 46, Sep 15

I take sertraline 100 mg daily. A friend gave me some tramadol for a bad tooth. Is that combination okay?

No—do not take tramadol with sertraline unless a clinician who knows your medications specifically prescribes and monitors it. The combination can raise the risk of serotonin syndrome and seizures, and you should never use someone else’s prescription opioid.

If you already took tramadol, do not take more. Seek emergency help for agitation/confusion, sweating, fever, diarrhea, muscle twitching or stiffness, fast heartbeat, tremor, seizure, severe drowsiness, or trouble breathing. In the U.S., call Poison Control at 1-800-222-1222 for individualized guidance; call emergency services for severe symptoms.

Contact a dentist promptly—the tooth may need treatment rather than pain medicine. Ask a pharmacist or clinician about safer options such as acetaminophen or ibuprofen based on your health history and other medicines. Do not abruptly stop sertraline.

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Sep 15, the whole day Question 46, every day

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No—**do not take tramadol with sertraline unless a clinician who knows your medications specifically prescribes and monitors it.** The combination can raise the risk of **serotonin syndrome** and **seizures**, and you should never use someone else’s prescription opioid.
If you already took tramadol, **do not take more**. Seek emergency help for agitation/confusion, sweating, fever, diarrhea, muscle twitching or stiffness, fast heartbeat, tremor, seizure, severe drowsiness, or trouble breathing. In the U.S., call Poison Control at **1-800-222-1222** for individualized guidance; call emergency services for severe symptoms.
Contact a dentist promptly—the tooth may need treatment rather than pain medicine. Ask a pharmacist or clinician about safer options such as acetaminophen or ibuprofen based on your health history and other medicines. **Do not abruptly stop sertraline.**

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