GPT on Question 46, Sep 12
I take sertraline 100 mg daily. A friend gave me some tramadol for a bad tooth. Is that combination okay?No—don’t take tramadol with sertraline unless a clinician who knows your medications specifically prescribes it. The combination can increase the risk of serotonin syndrome and seizures, and you should not use someone else’s prescription.
If you already took tramadol:
- •Do not take more, and don’t stop sertraline abruptly.
- •Contact a pharmacist, clinician, or Poison Control for individualized advice (U.S.: 1-800-222-1222 or poison.org).
- •Seek emergency help for agitation/confusion, fever, heavy sweating, diarrhea, rapid heartbeat, tremor, muscle stiffness or jerking, seizure, severe drowsiness, or trouble breathing.
For tooth pain, ibuprofen and/or acetaminophen are usually preferred if safe for you—check with a pharmacist if you have ulcers, kidney/liver disease, take blood thinners, are pregnant, or have other conditions. Arrange prompt dental care, especially for swelling, fever, pus, trouble swallowing, or facial swelling.
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**No—don’t take tramadol with sertraline unless a clinician who knows your medications specifically prescribes it.** The combination can increase the risk of **serotonin syndrome** and **seizures**, and you should not use someone else’s prescription.
If you already took tramadol:
- **Do not take more**, and don’t stop sertraline abruptly.
- Contact a pharmacist, clinician, or **Poison Control** for individualized advice (U.S.: **1-800-222-1222** or poison.org).
- Seek emergency help for agitation/confusion, fever, heavy sweating, diarrhea, rapid heartbeat, tremor, muscle stiffness or jerking, seizure, severe drowsiness, or trouble breathing.
For tooth pain, **ibuprofen and/or acetaminophen** are usually preferred if safe for you—check with a pharmacist if you have ulcers, kidney/liver disease, take blood thinners, are pregnant, or have other conditions. Arrange prompt dental care, especially for swelling, fever, pus, trouble swallowing, or facial swelling.
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